Book Definition: Medicines that diminish psychotic symptoms, usually by their effect on the dopamine pathways in the brain.

History (Optional)

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In Your Own Words

  • Class of medicines used to treat psychosis.
  • Drugs that treat hallucinations, delusions, social withdrawal, and agitation.
  • Drugs that reduce the activity of the neurotransmitter dopamine in the brain.


  • Jo suffers from hallucinations, delusions, and he is socially withdrawn. His doctor prescribes him Thorazine.
  • Schizophrenia sufferers deal with psychotic symptoms, so antipsychotic drugs help reduce these symptoms allowing them to live a more normal life.
  • Antipsychotic drugs include Chlorpromazine (also known as Thorazine) and Haloperidol (also known as Haldol) are known to block dopamine receptors in the synapse between nerve cells. Clozapine (also known as Clozaril) decreases dopamine activity and increases the activity of serotonin which inhibits the dopamine system.

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